Journal of Osseointegration 2019-09-25T11:50:11+02:00 Cristina Calchera Open Journal Systems <h1>Journal of Osseointegration</h1> <p>The aim of the<strong> Journal of Osseointegration</strong> in the Implant Dentistry field is to publish high quality contemporary, timely, innovative, interesting and clinically relevant information that will be used for improvement of the care of our patients. The rapid growth of research and more application of advanced clinical procedures has led us to start this new journey, that we hope will be a journey of success. The objective of all the people involved in this project will be to present the data in an accurate, fair and unbiased way. Each paper will be given the close attention that it merits and only manuscripts with well designed projects, conducted in a manner that follows sound scientific principles will be accepted. Also the rapidity of the reviewing process will be a key goal, this will be ensured by a web based submission and colse supervision on the reviewing process. A concerted effort will be made to shorten the time between submission, correction, acceptance of the manuscript, online publication, and print publication. We aim also for a high standard of technical editing, which serves to ensure the consistency of the content style and the fact that the language should be as unambiguous and clear as possible. Manuscripts dealing with basic research, biomaterials, tissue engineering techniques, clinical research and technical innovations will be accepted. The help of all involved people will be of outstanding relevance in achieving this mission.<br><em>Access to the contents of the Journal of Osseointegration is open and free to all users: this is our small contribution to global exchange of knowledge. Users can read, download, copy, distribute, print, search, or link to the full texts of our articles.</em></p> Evaluation of the health of the peri-implant tissues around immediately placed dental implants in aggressive periodontitis patients versus periodontally healthy individuals in the maxillary esthetic zone: Controlled clinical trial 2019-09-25T11:50:11+02:00 N. M. Yussif A. R. Abdel Rahman M. Darhous <p class="p1"><span class="s1"><strong>Aim </strong>To evaluate the health condition of the immediately placed dental implants in aggressive periodontitis patients compared to periodontally healthy individuals after 12 months of follow up.</span></p> <p class="p1"><span class="s1"><strong>Materials and methods</strong> Following atraumatic tooth extraction, 70 implants were placed in two study groups: Thirty-five implants replaced hopeless teeth in aggressive periodontitis patients (test group) and thirty-five implants replaced periodontally healthy unrestrorable teeth (control group).&nbsp;</span></p> <p class="p1"><span class="s1"><strong>Results </strong>After 12 months, there were no dropouts in both groups. The criteria of the health scale showed 97.17% success in the test group versus 100% in the control group. Due to peri-implant mucosistis, only 2.85% implants in the test group showed satisfactory survival rate. It was also found that 20% of the inserted implants in both groups were covered with bone during the second stage surgery. Lack of pain, mobility, exudate and suppuration with no incidence of peri-implant diseases were clearly detected in both groups indicating the success rate. There was no statistical significant difference between the results in both groups. </span></p> <p class="p1"><span class="s1"><strong>Conclusions</strong><span class="Apple-converted-space">&nbsp; </span>The current study highlights that immediate placement did not affect health and survival of the implants in aggressive periodontitis patients. Nearly equal results were reported between periodontally healthy and periodontally affected patients. Long- term follow up studies are recommended to examine the failure rate that could not be reported in the current short-term study. </span></p> 2019-09-25T09:56:08+02:00 ##submission.copyrightStatement## Is immediate implant placement advantageous for the management of aggressive periodontitis patients in maxillary esthetic zone? An update of systematic reviews 2019-09-20T11:40:57+02:00 N Yussif A. R. Abdel Rahman <p class="p1"><span class="s1"><strong>Aim </strong>To determine the<span class="Apple-converted-space">&nbsp; </span>clinical safety, survival and success of the immediate dental implant placement in aggressive periodontitis patients.</span></p> <p class="p1"><span class="s1"><strong>Materials and methods</strong> In April 2019, Pubmed, Cochrane central database, Web of Science, Lilacs and hand search were searched with no restrictions for language, publication date or follow up period. All types of prospective studies reporting the prognosis of immediate implant placement were included. Outcomes were implant survival rate, complications during placement and postoperatively and marginal bone loss around implants.&nbsp;</span></p> <p class="p1"><span class="s1"><strong>Results</strong> After screening of the titles, abstracts and full text of the reported studies, none of those met the pre-determined inclusion criteria.</span></p> <p class="p1"><span class="s1"><strong>Conclusions </strong>There was no sufficient evidence regarding the survival rate of immediately placed dental implants in patients affected with aggressive periodontitis. Long term prospective double armed clinical studies are recommended.</span></p> 2019-09-19T11:38:39+02:00 ##submission.copyrightStatement## Bond strength to radicular dentin of two experimental luting cements 2019-09-18T11:35:59+02:00 Giulia Bonarini Edoardo Ferrari Cagidiaco Nicola Discepoli <p class="p1"><span class="s1"><strong>Aim </strong> The aim of this study was to test two different of experimental cements based on two types of polymerization techniques comparing them with one already well known in the market.</span></p> <p class="p1"><span class="s1"><strong>Materials and methods</strong><span class="Apple-converted-space">&nbsp; </span>Thirty intact central incisors, extracted for periodontal reasons, were selected and endodontically treated, then were randomly divided into 3 groups of 10 samples: Group 1, light cured composite experimental material with self-etch adhesive and dual polymerization activator; Group 2, dual experimental core build-up with self-etch adhesive and dual-polymer activator; Group 3 (control group), dual cement with self-etch adhesive and dual polymerization activator. One fiber post was luted into the root canal strictly following manufacturer’s instructions. Each sample was cut in slices in order to perform the push-out bond strength test with a testing machine. To express the bond strength in MegaPascals (MPa), the breaking load recorded in Newton (N) was divided by the area of the bonded interface (A) in mm<sup>2</sup>. The area of the bond interface was calculated as the area of the surface of a truncated cone using the formula: A = π (R + r) [h2 + (Rr) 2] 1/2, where R represents the major radius of the coronal post, r represents the minor radius of the apical post and h is the thickness of the slice in millimeters. The diameters and thickness of the slice were measured individually using a digital caliper with 0.01 mm precision. After the test, each slide was observed to detect the type of failure and classified as adhesive between cement and dentin (AD); adhesive between the cement and the post (AP); fracture of the sample, cohesive inside the post and dentin (FR); cohesive in cement (CC); mixed (M).</span></p> <p class="p1"><span class="s1"><strong>Results</strong><span class="Apple-converted-space">&nbsp; </span>Group 2 recorded the highest values of adhesion strength,<span class="Apple-converted-space">&nbsp; </span>group 1 the lowest. There were no statistically significant differences among groups 1 and 2 and controls. The most common failure mode was the mixed one and the less frequent was the adhesive type between the post and the cement.</span></p> <p class="p1"><span class="s1"><strong>Conclusions</strong><span class="Apple-converted-space">&nbsp; </span>Within the limitations of this study, it can be concluded that the bond strength of experimental resin cements is comparable to that of a cement marketed by the same manufacturer, used here as a control and well known in the market. </span></p> 2019-09-17T13:03:44+02:00 ##submission.copyrightStatement## Interaction of dental pulp stem cells in bone regeneration on titanium implant. An in vitro study 2019-09-13T11:25:12+02:00 Sushmita Palanisamy chethan kumar J.S chethan hegde Basan Gowda. S. Kurkalli <p class="p1"><span class="s1"><strong>Aim</strong> To investigate <em>in vitro</em> interaction of dental pulp stem cells (DPSCs) in bone regeneration on titanium implants. </span></p> <p class="p1"><span class="s1"><strong>Materials and methods </strong>Dental pulp tissue collected from<span class="Apple-converted-space">&nbsp; </span>extracted teeth without infection was used to obtain DPSCs. The biocompatibility of titanium implant was studied by culturing the DPSCs in conditioned media obtained by incubating the titanium implants for 72 hours. Following which the interaction of DPSCs on titanium implants was checked by wrapping the DPSCs cell sheet on SLA (sandblasted large grit acid etched) treated and smooth implants. </span></p> <p class="p1"><span class="s1"><strong>Results<span class="Apple-converted-space">&nbsp; </span></strong>Cytotoxicity test revealed that the SLA treated implants were biocompatible and did not affect the proliferation rate of DPSCs. Osteogenic study with titanium implant revealed DPSCs have the capacity to undergo osteogenic differentiation in the presences of titanium implants.</span></p> <p class="p1"><span class="s1"><strong>Conclusions </strong>This study postulates that it is possible to construct a biologically modified implant by wrapping the dental stem cell sheet around commercially available implants in order to improve the process of osseointegration as the implant- stem cell complex contains all the factors required for osseointegration.</span></p> 2019-09-13T09:32:40+02:00 ##submission.copyrightStatement##