https://doi.org/10.23805/JO.2025.615
Comparison Of Superoxide Dismutase Levels Among Patients With Diverse Surface Treated Dental Implants: A Prospective Clinical Study
Accepted: 5 January 2024
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Background: Implants have evolved in terms of shape, size, and surface in order to optimize the success rate. Exploring the antioxidant levels around different surface treated dental implants is essential to improve the performance of implants. The present study was to detect and measure the level of superoxide dismutase (SOD), which is an antioxidant enzyme among patients with sandblasted acid-etched and anodized surface dental implants.
Materials and Methods: In this prospective clinical study, 78 patients who had undergone implant placement for missing single posterior tooth in mandible using sandblasted acid-etched and anodized surface dental implants during August 2019 - December 2019 were enrolled and were categorized into Group 1: SLA (n=27), Group 2: SLActive (n=26), Group 3: TiUnite (n=25) based on the surface modification of the implants. Peri-implant crevicular fluid (PICF) was collected and SOD was quantified using ELISA kit. One-way ANOVA followed by Tukey’s HSD post hoc was done for statistical analysis. For intragroup comparison, paired t test was used.
Results: SOD level in group 3 implants was significantly lower than group 1 and group 2 (p≤0.05). On pairwise comparison between the groups, there was a statistically significant difference both at baseline (p≤0.05) and 1-year follow up (p≤0.05). Intragroup comparison revealed a statistically significant difference from baseline in all the three groups (p≤0.05).
Conclusion: Superoxide dismutase level in peri-implant crevicular fluid was low around TiUnite dental implant as compared to SLA and SLActive implants.
Keywords: Acid-etched, Anodization, Dental implant, Oxidative stress, Sandblasting, Superoxide dismutase
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