Immediate loaded full-arch maxillary rehabilitations in younger vs elderly patients: a comparative prospective study with 6-year follow up

Submitted: 17 September 2024
Accepted: 4 November 2024
Published: 24 April 2025
Abstract Views: 26
PDF: 19
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Aim The aim of this prospective comparative study was to assess whether age has an influence on implant survival in patients treated with implants rehabilitated according to the All-on-4 treatment concept.

Materials and methods A prospective study was performed with two edentulous patient groups: a younger group (n = x; average age 45 years, 35-50 years) and an older group (n = x; average age 68 years, 60-80 years). Implant and prosthetic failure, biological prosthetic complicance, peri-implant marginal bone level changes for survival rates. To compare marginal bone levels between younger and older patients groups at 6 months and yearly until the 6-year follow-up, Student's t-tests were applied at a significance level of p < 0.05.

Results Fifty-four patients met the eligibility criteria and were included in the study among 78 patients screened; a total of of 216 implants were placed in 54 patients (table 1) and, in total, 54 “all-on-four” rehabilitations were delivered. Implants failure was registered in four patients (4 of 216 fixtures), 2 in YG patient and 2 in a OG; So, an implant failure rate of 1.85% was reported in each group. Peri-implantitis was observed in 7 of 216 implants (3.24%) and 4 of 54 patients (7.41%) (2 from YG and 2 from OG) at the 6-year follow-up. At the 6-year radiographic evaluation, peri-implant crestal bone loss averaged 1.01 ± 0.93 mm for OG and 0.85 ± 1.04 mm for YG. Three of 54 fixed provisional prostheses were fractured during the observation period, representing a prosthetic survival rate of 94.45%

Conclusion At 6 years of follow-up the significant statistical difference in outcome measures between the two groups is not significant so all-on-4 rehabilitation is indicated in elderly patients in order to improve their quality of life.

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Nagni, M., Tetè, G., D’Orto, B., Romanos, G. E., Polizzi, E., & Gherlone, E. F. (2025). Immediate loaded full-arch maxillary rehabilitations in younger vs elderly patients: a comparative prospective study with 6-year follow up. Journal of Osseointegration. https://doi.org/10.23805/JO.2025.691